Celebrating Scholarship and Creativity Day (2018-)

Document Type

Poster

Publication Date

4-30-2026

Disciplines

Biology | Medicine and Health Sciences

Advisor

Demelza Larson

Abstract

Histology is the study of microscopic tissue structures and is used to understand the function of tissues and visualize the cellular organization within them. It is an important tool in biology and medicine, used for diagnosing disease (i.e., cancers, infections, inflammatory diseases, etc.) and studying organ structure and function. The goal of this poster is to compare preparation and staining techniques, specifically paraffin versus frozen sectioning methods, along with Masson’s trichrome versus hematoxylin and eosin (H&E) staining. These methods differ in processing time, tissue preservation, and the level of detail they reveal under a microscope. This project uses small intestines of mice as the tissue of focus. Small intestine tissue has distinct layering and specialized structures, such as villi and glands, that can be seen under a microscope using H&E and Masson’s trichrome staining. By examining how different preparation and staining techniques highlight different features, this poster examines the pros and cons of each technique.

Download

Share

COinS