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Analytical Chemistry | Chemistry | Physical Sciences and Mathematics


Brian Johnson, Chemistry


Iodine is an overlooked but incredibly important micronutrient, especially with regard to early fetus development. The United States does not mandate salt iodization, so widely consumed processed foods are not likely to contain iodized salt, which may potentially put the population at risk for developing iodine deficiencies. Therefore, the purpose of this study is to correspond iodine intake to iodine status and establish effective methods for determining a relationship between the two. Subjects (n=23) completed a food survey and supplied 50mL urine samples to compare an estimated average daily iodine intake based on foods over the course of a week and urinary iodine content determined via spectrophotometric analysis of the Sandell-Kolthoff reaction. Most subjects fell into the optimal intake and urinary iodine categories, but the survey inconsistently correlated intake and urine categories, most likely due to the use of a single spot urine sample. Future studies should investigate more representative intake surveillance, potentially through the use of 24-hour recalls or food diaries, and more representative urine sample collection methods, as with a 24-hour collection or a control for hydration.